Blight by far! I can defend fairly well against attacks, volcanic eruptions, starving, and missles. People are dying is more of a "WTF?!" reaction for me...and enemy unit sighted...I don't even hear it when it's said anymore. Whenever the blight pops up on the map, by first thought is "OH s***!" because there is nothing I can do to delay it. Blight walls don't work unless you made them hella thick, and thereby doomed yourself anyway becuase of wasted resources.
I just got a map idea...