Copy the BITMAPS, MUSIC, and VIDEOS directories from your Outpost CD into the same directory where you installed the game, usually C:\SIERRA\OUTPOST.
Change the OUTPOST.INI file located in the same directory where the game has been installed to point to directories on your hard drive where you have copied the BITMAPS, MUSIC, and VIDEOS. When you are done the first part of the file should look something like this…
[general]
opimage=C:\SIERRA\OUTPOST\bitmaps;C:\SIERRA\OUTPOST\videos;C:\SIERRA\OUTPOST\music
falseMap=off
Leave the other settings as they are. Now the game will play without the CD. This actually was an install option in the original release of the game – later removed in the last (Sierra Classics) edition. Hope this helps.